NVIDIA48 GB VRAM864 GB/s$0.7/hr

Mixtral 8x22B (MoE) on L40S 48GB: Does It Fit, How Fast, What It Costs

Mixtral 8x22B (MoE) at AWQ 4-bit needs 77.6 GB for its weights and 92.6 GB in total at 8K context with 8 concurrent users. That means it needs 2× L40S 48GB. Every figure is computed by tokcalc's open-source capacity model.

Fits?
Yes, 2×
92.6 GB needed / 96 GB available
Decode speed
39.17
tok/s per stream
Aggregate
940.0
tok/s @ 8 concurrent
Cost / 1M tokens
$0.4137
2× L40S 48GB

L40S 48GB has no NVLink, so 2-way tensor parallelism runs over PCIe. tokcalc applies a flat 0.85× multi-GPU efficiency factor for this, which is realistic for NVLink-equipped datacenter cards but optimistic for PCIe scale-out — treat the throughput and cost figures for this configuration as an upper bound, and measure before committing.

What changes as you add L40S 48GBs
Tensor-parallel degree vs VRAM, throughput, and cost. Cost scales linearly with GPU count; decode throughput scales near-linearly too, so cost per token stays roughly flat.
GPUsTotal VRAMVRAM neededDecode tok/sAggregate tok/sTTFTCost / 1M tokFits?
1× L40S48 GB92.6 GB0.0000.000——✗
2× L40S96 GB92.6 GB39.17940.07.03 s$0.4137✓
4× L40S192 GB92.6 GB78.3437603.53 s$0.2068✓
8× L40S384 GB92.6 GB156.7150411.78 s$0.1034✓
Concurrency vs context length
On 2× L40S 48GB at AWQ 4-bit. KV cache scales linearly with context, so this is the number of users your GPUs can actually serve.
ContextConcurrent usersKV per requestFits?
4K19962.1 MB✓ fits
8K91.88 GB✓ fits
33K27.52 GB✓ fits
66K115.03 GB✓ fits
131K030.06 GB✗ does not fit
Other GPUs that run Mixtral 8x22B (MoE)
Same workload, same quantization — ranked by value (tokens per dollar-hour).
GPUGPUsAggregate tok/sCost / 1M tok
RTX 5090 32GB4×7799$0.0712
A100 80GB SXM42×2176$0.3064
H100 SXM5 80GB2×3645$0.3811
AMD MI300X 192GB1×1696$0.4095
AMD MI325X 288GB1×1920$0.5064
Intel Gaudi 3 128GB1×1056$0.5261
Frequently asked questions

Can Mixtral 8x22B (MoE) run on L40S 48GB?

Yes, but it needs 2× L40S 48GB. At AWQ 4-bit the total footprint is 92.6 GB (77.6 GB of weights plus 15.0 GB of KV cache at 8K × 8 concurrent users), against 96 GB of available VRAM across 2 GPUs.

How fast is Mixtral 8x22B (MoE) on L40S 48GB?

39.17 tokens/sec per stream and 940.0 tok/s aggregate with continuous batching at 8 concurrent users. Time to first token is 7.03 s, and inter-token latency is 25.5 ms.

What does Mixtral 8x22B (MoE) on L40S 48GB cost per million tokens?

$0.4137 per 1M output tokens at 2× L40S 48GB ($0.7000/hr). That is the marginal hardware cost — add idle capacity, ops, and egress for the real figure.

How much VRAM does Mixtral 8x22B (MoE) need on L40S 48GB?

77.6 GB for the weights at AWQ 4-bit, plus 15.0 GB of KV cache for 8 concurrent requests at 8K context — 92.6 GB total. Every extra concurrent user at long context costs more, so leave headroom.

Is L40S 48GB the right choice for Mixtral 8x22B (MoE)?

It works. Compare $0.4137 per 1M tokens against the alternatives below — the cheapest option that fits the same workload is 8× RTX 4080 16GB at $0.0534, and the fastest is 4× Cerebras CS-3 (WSE-3) at 87040 tok/s.

Adjust the workload yourself

Same formulas, your context length, concurrency, and quantisation.

Open in calculator