NVIDIA32 GB VRAM1,792 GB/s$0.5/hr

Qwen 2.5 72B on RTX 5090 32GB: Does It Fit, How Fast, What It Costs

Qwen 2.5 72B at FP8 (E4M3) needs 72.7 GB for its weights and 94.2 GB in total at 8K context with 8 concurrent users. That means it needs 4× RTX 5090 32GB. Every figure is computed by tokcalc's open-source capacity model.

Fits?
Yes, 4×
94.2 GB needed / 128 GB available
Decode speed
81.71
tok/s per stream
Aggregate
3922
tok/s @ 8 concurrent
Cost / 1M tokens
$0.1416
4× RTX 5090 32GB

RTX 5090 32GB has no NVLink, so 4-way tensor parallelism runs over PCIe. tokcalc applies a flat 0.85× multi-GPU efficiency factor for this, which is realistic for NVLink-equipped datacenter cards but optimistic for PCIe scale-out — treat the throughput and cost figures for this configuration as an upper bound, and measure before committing.

What changes as you add RTX 5090 32GBs
Tensor-parallel degree vs VRAM, throughput, and cost. Cost scales linearly with GPU count; decode throughput scales near-linearly too, so cost per token stays roughly flat.
GPUsTotal VRAMVRAM neededDecode tok/sAggregate tok/sTTFTCost / 1M tokFits?
1× RTX32 GB94.2 GB0.0000.000——✗
2× RTX64 GB94.2 GB0.0000.000——✗
4× RTX128 GB94.2 GB81.7139225.71 s$0.1416✓
8× RTX256 GB94.2 GB163.4156892.87 s$0.0708✓
Concurrency vs context length
On 4× RTX 5090 32GB at FP8 (E4M3). KV cache scales linearly with context, so this is the number of users your GPUs can actually serve.
ContextConcurrent usersKV per requestFits?
4K411.34 GB✓ fits
8K202.68 GB✓ fits
33K510.74 GB✓ fits
66K221.47 GB✓ fits
131K142.95 GB✓ fits
Other GPUs that run Qwen 2.5 72B
Same workload, same quantization — ranked by value (tokens per dollar-hour).
GPUGPUsAggregate tok/sCost / 1M tok
A100 80GB SXM42×1094$0.6092
H100 SXM5 80GB2×1833$0.7577
AMD MI300X 192GB1×853.0$0.8142
L40S 48GB2×472.8$0.8226
AMD MI325X 288GB1×965.6$1.01
Intel Gaudi 3 128GB1×531.1$1.05
Frequently asked questions

Can Qwen 2.5 72B run on RTX 5090 32GB?

Yes, but it needs 4× RTX 5090 32GB. At FP8 (E4M3) the total footprint is 94.2 GB (72.7 GB of weights plus 21.5 GB of KV cache at 8K × 8 concurrent users), against 128 GB of available VRAM across 4 GPUs.

How fast is Qwen 2.5 72B on RTX 5090 32GB?

81.71 tokens/sec per stream and 3922 tok/s aggregate with continuous batching at 8 concurrent users. Time to first token is 5.71 s, and inter-token latency is 12.2 ms.

What does Qwen 2.5 72B on RTX 5090 32GB cost per million tokens?

$0.1416 per 1M output tokens at 4× RTX 5090 32GB ($0.5000/hr). That is the marginal hardware cost — add idle capacity, ops, and egress for the real figure.

How much VRAM does Qwen 2.5 72B need on RTX 5090 32GB?

72.7 GB for the weights at FP8 (E4M3), plus 21.5 GB of KV cache for 8 concurrent requests at 8K context — 94.2 GB total. Every extra concurrent user at long context costs more, so leave headroom.

Is RTX 5090 32GB the right choice for Qwen 2.5 72B?

It works. Compare $0.1416 per 1M tokens against the alternatives below — the cheapest option that fits the same workload is 8× RTX 4080 16GB at $0.1062, and the fastest is 4× Cerebras CS-3 (WSE-3) at 43774 tok/s.

Adjust the workload yourself

Same formulas, your context length, concurrency, and quantisation.

Open in calculator